Articles & Technical Resources
In-depth articles on calibration science, laboratory compliance, measurement standards, and best practices — written by the technical team at Femto Scientific.
Mass Weight Set Calibration: ASTM & OIML Standards, Measurement Uncertainty, and Pharmaceutical Compliance
A comprehensive guide to ASTM E617 Classes 0–7, OIML R 111 Classes E1–M3, the mass comparator calibration process, buoyancy correction, NIST traceability, measurement uncertainty, and USP <41>, USP <1251>, and GMP compliance requirements — including 35 FAQs.
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Autoclave Sterilization Calibration & Validation: A Complete Guide
F&sub0; value calculation, temperature distribution mapping, Bowie-Dick testing, IQ/OQ/PQ validation protocols, and FDA 21 CFR / USP <1229> compliance requirements for pharmaceutical, biotech, and clinical laboratory autoclaves.
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Automated Liquid Handling Systems: Robotic Pipetting, 96-Well & 384-Well Workstations, and Laboratory Automation
How automated liquid handling systems work, accuracy and precision verification, tip-based vs. non-contact dispensing, and ISO/IEC 17025 calibration for robotic pipetting stations in pharmaceutical and genomics laboratories.
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Biosafety Cabinet Certification: NSF 49, HEPA Integrity Testing, Chemical Fume Hoods & Cleanroom Certification
NSF/ANSI 49 certification testing, HEPA filter integrity testing, airflow velocity measurement, chemical fume hood face velocity verification, and regulatory requirements for biosafety cabinet and cleanroom certification.
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Refrigerator & Freezer Calibration: Ultra-Low Temperature, Cryogenic Storage, Temperature Mapping & Pharmaceutical Compliance
Temperature mapping methodology, NIST-traceable probe calibration, −80 °C ultra-low freezer monitoring, and ISO/IEC 17025 compliance for pharmaceutical cold storage, biorepository management, and cryogenic systems.
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Humidity and Temperature Calibration: A Complete Technical Guide
How humidity sensors work, multi-point calibration procedures, measurement uncertainty, NIST traceability, and GMP/FDA requirements — a technical guide to accredited humidity and temperature calibration for pharmaceutical, clinical, and research laboratories.
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What Is pH Meter Calibration? A Technical Guide for Laboratory Professionals
Electrode slope, buffer traceability, temperature compensation, and Nernst response explained — how ISO/IEC 17025 accredited pH meter calibration satisfies GMP, FDA, CAP, and CLIA requirements for laboratory compliance programs.
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What Is HPLC Preventative Maintenance? IQ/OQ/PQ, Validation & GMP Compliance Guide
A comprehensive guide to HPLC preventative maintenance, IQ/OQ/PQ qualification procedures, GMP and FDA 21 CFR Part 11 requirements, and audit-ready documentation for pharmaceutical, biotech, and clinical laboratories.
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What Is Thermal Cycler Calibration? A Technical Guide for PCR and qPCR Laboratories
Block temperature accuracy, well-to-well uniformity, ramp rates, and heated lid verification explained — why ISO/IEC 17025 accredited PCR thermal verification satisfies CAP, CLIA, and cGMP compliance requirements.
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What Is CO2 Incubator Calibration? A Technical Guide for Laboratory Professionals
A technical guide to CO2 incubator calibration: performance drift, IRGA vs. thermal conductivity sensors, temperature mapping, and how ISO/IEC 17025 accredited calibration satisfies FDA, CAP, and CLIA requirements.
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What Is Temperature Calibration? The Complete Guide for Laboratory Professionals
Thermocouple and RTD calibration standards, calibration bath methodology, ITS-90 traceability, measurement uncertainty calculation, and GMP, FDA, CAP, and CLIA compliance requirements for laboratory temperature calibration programs.
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What Is UV-Vis Spectrophotometer Calibration? The Complete Guide for Laboratory Professionals
Wavelength accuracy, photometric accuracy, stray light performance, and linearity explained — how ISO/IEC 17025 accredited UV-Vis, Nanodrop, and microplate reader calibration satisfies GLP, GMP, and USP requirements.
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What Is Centrifuge Calibration? A Technical Guide for Laboratory Professionals
RPM, timer, and temperature verification explained — why centrifuges drift and how ISO/IEC 17025 calibration satisfies FDA 21 CFR, CAP, and CLIA requirements.
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What Is Thermometer Calibration? A Technical Guide for Laboratory Professionals
Temperature drift, ASTM E220, ASTM E77, ITS-90, and ASTM E1137 standards explained — how ISO/IEC 17025 accredited thermometer calibration satisfies GMP and clinical regulatory requirements.
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Ensuring Precision and Compliance: The Importance of Balance Calibration with ISO 17025 and USP 41 Standards
Balance calibration is a critical process in any laboratory. The accuracy of measurements directly impacts product quality, regulatory compliance, and the integrity of experimental data — especially under ISO/IEC 17025 and USP 41.
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The Crucial Role of Pipette Calibrations in Ensuring Laboratory Excellence
Precision is non-negotiable in scientific research. This article explores how pipette calibration safeguards experimental accuracy, data integrity, regulatory compliance, and the overall reputation of a laboratory.
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